Solving Protein Folding Problem using Elitism-Based Compact Genetic Algorithm

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چکیده

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15 صفحه اول

Towards Solving the Inverse Protein Folding Problem

Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies and underlies the inverse protein folding problem. Herein, we outline our theories for fold-recognition in the “twilight-zone” of sequence similarity (<25% identity). Our analyses demonstrate that structural sequence profiles built using Position-Specific Scoring Matrices (PSSMs) significantly o...

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ژورنال

عنوان ژورنال: Journal of Computer Science

سال: 2008

ISSN: 1549-3636

DOI: 10.3844/jcssp.2008.525.529